• -·- ----------- ------- ----- -----·-__ ---- - ------------------·- ---·- ' 00 t1 00 0 0 •0 n 0 0 0 0 0 0 I 0 0 0 0 0 r 0 0 o 00 ' 0 0 I ' I ' 0 00 • 00 ' Q 0 0 0 ' 0 ti' Ii 0 ' I 00 • I • ' ••' ST PO - Mz•s Mildred Caretb • FSD - Mrs R Ellis 0 HEl - Hugh V Bi 10 '0WS Medical Admi al 1 r tion Officer • • WashingtoD Oniver ity R ttu st for Contr ct • • • • r • I It is reque ed that a contr ct be established between th D pa rtment the George Washington University - Vasbington D C 0006 for support • • I -1 of esearch p1-ojec t ntitled CrroGEHETIC EVALUATION OF MUTAGENIC EXPOSURE hereby coded peripheral blood samples fx'Om pre- and post- • ' • ' • • mutagenlc exposure li'ill be studied for cosparative gx'Ovt h capacity and chromoscaal composition through phytohemagglut nin stimulated lymphocyt cultures Analysis viJ l be by photomicrographs printed at 20 000 magnlf i- ca ion · · • Tbe fol loving servic s personnel facilities and equipment' will be provided by the University • • I ' - • • • - PI RSO HNEt · · Frinc ipal Investigator vfll be Cec il B Jacobsen M D of the Human Cytogenetic Research Laboratot y • It will hi responsibility to supervise all experimental proce ing and a ysis of th coded sara- ples • • FACILITIES Am tQJIFMDlT Two fwlc tional cytogeDetic laboratories 1 nder the direc ion of tbe Principal Investigator at the University Adequate space and equipnen't is available to ful fi J this coDtract • • • • • • TRAHSPOR ATIOH OF BLOOD SAMPLES The coded peripheral blood samples will be tran - • pox•ted by UJ iversity personnel f1-om the clinical labo- I ratory facilities of the Medical Divisi0n Dep - wlen't • of State to tbe Unlver ity Hospi'ta l laboratories in an hisula'ted containa to be pt vided by the Univer ity All records and photographic terial vil be returned to the Medical Divi ion D pac•twent of State upon request • • ¾ • • • • • • RESEARCH TECIDlIQUI S • •• ' I • C • ' • 00 00 0 0 C 0 0 I 0 00 0 0 0 0 00 0 0 0 0 0 0 0 0 0 0 0 0 0 • 0 0 I 0 0 0 0 J 0 oJ ll 0 J Pf-lOT l OPY FRO GERALD F RD LIB - -- - ·- - • ----------------------------- ---- ------------__ _ --------- ---- • 1 1 • • • о - о 1 ' оо о о оо о о о 00 ООО • о о о о о ' о о о о о 00 о -- О о о о оо о с о о о о 2 о Q 1 О о о ' • 1 • tj 11• r t С · - 1 t 11 • 11 •1••• • о о • • • • • Тhе rates and costs involved in this contract are falr and reason­ aЬle and are the staDdard chargeз for this type of service ln thi� area • Cos�s of tЫs contract vill Ье charged against • OЫigation 1 • • • � you have any questions regarding �his contract or need addi�iona l info11nat ion рlеазе notiry me • • • •• • 1 • 1 - � 1 ••l ' •1 СС FSD - Мrs Rозе EJli� - • 1 1 1 • • • • • 1 -1 -- tL � ' 1 • •• • 0 НЕD ERН ggs erh • 00 о о о с• Q ООО о о о uo 6 о о ou с�о ' ------- ---- -·-------- _ • 1 '17 бб о о о 00 о ООО о о ---·-- о о 00 о 1 � о о о __ о о о о J Q о· о 1 о J о о s J J о J • Appropriatlon ----------- • Allotment • • • • •• ' Тhе George Washington Univerзity s not tbe sole source however Medical Division's phyзiciana Ьelieve tbat tbe Ьest conзulting services re availaЬle a t the University for th1s specific Ыооd рrоЫеш • • о - • • 1 1 • о ' • 'IЪе cos-t per- ianalys s а Ьased on one culture unit for the inltia l ha nd ling counting·and settlng of -the or ginal cult ПЧIS with approxi111ately ью cultures units for suЬseq'1ent 48 and 72 hour sacrificing ТЬrее pbotographic unlts per spec шen w ll Ъе provided Тhе total cost of these six units is $150 00 per speci en Тhе proposed contract wi11 соеыаеnсе on Febru ary l 1966 and extend through December Зl 1966 at А total cost of $6 988 00 for forty-six specimens Ir additional spec шens are to Ье examined 'the Univ-ersity v111 Ъе reimbursed at the rate of $1�0 ОО for each sucb specimen Cost es'tlmёltes for vhich 'the cont rac't ai ad average spec imen amoun1 s -were derived are artached • • ' RESEARCH ТECНNI JES All reaearch techniques wi11 Ье cac·ttied out Ьу the Universi'ty as stated on tЪе attached de­ acr 1ption • • 1 •• j• i '1 •r 1 о ООО о о • •• РНОТ СОРУ FROM GERALD F�RD Llft ARY - --• - •- - ____ _ -- _ _ ___________ - -